GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs9902453 | 1 | rs62070270 | chr17:28263980 | SSH2 | chr17:27952965-28257018:- | 0.33 | 7.38 | 7.23E-13 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs62070270 | chr17:28263980 | TP53I13 | chr17:27895739-27900174:+ | 0.2 | 5.42 | 9.29E-8 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs62070312 | chr17:28438877 | ANKRD13B | chr17:27916801-27941778:+ | 0.36 | 8.84 | 1.89E-17 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs62070312 | chr17:28438877 | CORO6 | chr17:27941774-27948441:- | 0.5 | 11.79 | 2.38E-28 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs62070312 | chr17:28438877 | EFCAB5 | chr17:28256874-28435469:+ | 0.59 | 11.2 | 5.24E-26 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs62070312 | chr17:28438877 | GIT1 | chr17:27900487-27916610:- | 0.29 | 6.73 | 4.98E-11 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs62070312 | chr17:28438877 | LRRC37B2 | chr17:28903483-28992715:+ | 0.18 | 3.86 | 0.00013 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs62070312 | chr17:28438877 | SSH2 | chr17:27952965-28257018:- | 0.36 | 8.34 | 7.84E-16 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs62070312 | chr17:28438877 | TP53I13 | chr17:27895739-27900174:+ | 0.21 | 5.68 | 2.31E-8 | Coffee consumption (cups per day) |
| THCA | cis | rs8077577 | 1 | rs62073605 | chr17:18066791 | FAM106A | chr17:18427880-18430160:- | -0.26 | -3.72 | 0.000219 | Obesity-related traits |
| THCA | cis | rs8077577 | 1 | rs62073605 | chr17:18066791 | FAM83G | chr17:18874382-18908060:- | -0.13 | -3.4 | 0.000718 | Obesity-related traits |
| THCA | cis | rs8077577 | 1 | rs62073605 | chr17:18066791 | LLGL1 | chr17:18128936-18148186:+ | -0.14 | -4.03 | 6.56E-5 | Obesity-related traits |
| THCA | cis | rs8077577 | 1 | rs62073605 | chr17:18066791 | LOC220594 | chr17:18414577-18445234:- | -0.32 | -4.09 | 5.03E-5 | Obesity-related traits |
| THCA | cis | rs8077577 | 1 | rs62073605 | chr17:18066791 | MYO15A | chr17:18012020-18083115:+ | 0.2 | 3.64 | 0.000303 | Obesity-related traits |
| THCA | cis | rs8077577 | 1 | rs62073606 | chr17:18069142 | FAM106A | chr17:18427880-18430160:- | -0.26 | -3.72 | 0.000219 | Obesity-related traits |